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Target
Galanin receptor type 3
Ligand
BDBM50187923
Substrate
n/a
Meas. Tech.
ChEMBL_368823 (CHEMBL864918)
Ki
17±n/a nM
Citation
 Konkel, MJ; Lagu, B; Boteju, LW; Jimenez, H; Noble, S; Walker, MW; Chandrasena, G; Blackburn, TP; Nikam, SS; Wright, JL; Kornberg, BE; Gregory, T; Pugsley, TA; Akunne, H; Zoski, K; Wise, LD 3-arylimino-2-indolones are potent and selective galanin GAL3 receptor antagonists. J Med Chem 49:3757-8 (2006) [PubMed]  Article 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM50187923
Synonyms:
1,3-dihydro-1-phenyl-3-[[3-(trilfluoromethyl)phenyl]imino]-2H-indol-2-one | 1-(phenyl)-3-{[3-(trifluoromethyl)phenyl]azamethylene}benzo[d]azolidin-2-one | CHEMBL210288
Type:
Small organic molecule
Emp. Form.:
C21H13F3N2O
Mol. Mass.:
366.3359
SMILES:
FC(F)(F)c1cccc(c1)\N=C1\C(=O)N(c2ccccc12)c1ccccc1
Structure:
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