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Target
Beta-lactamase
Ligand
BDBM37510
Substrate
n/a
Meas. Tech.
ChEMBL_434809 (CHEMBL917037)
IC50
>100000±n/a nM
Citation
 Feng, BY; Simeonov, A; Jadhav, A; Babaoglu, K; Inglese, J; Shoichet, BK; Austin, CP A high-throughput screen for aggregation-based inhibition in a large compound library. J Med Chem 50:2385-90 (2007) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC
Type:
Protien
Mol. Mass.:
41561.62
Organism:
Escherichia coli
Description:
P00811
Residue:
377
Sequence:
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
  
Inhibitor
Name:
BDBM37510
Synonyms:
6-methyl-2-phenyl-1H-quinolin-4-one | 6-methyl-2-phenyl-4-quinolone | CHEMBL16223 | MLS000112473 | SMR000108387 | cid_730810
Type:
Small organic molecule
Emp. Form.:
C16H13NO
Mol. Mass.:
235.2805
SMILES:
Cc1ccc2nc(cc(O)c2c1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: