Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, heart
Ligand
BDBM50212886
Substrate
n/a
Meas. Tech.
ChEMBL_455934 (CHEMBL887935)
Ki
220±n/a nM
Citation
 Sulsky, R; Magnin, DR; Huang, Y; Simpkins, L; Taunk, P; Patel, M; Zhu, Y; Stouch, TR; Bassolino-Klimas, D; Parker, R; Harrity, T; Stoffel, R; Taylor, DS; Lavoie, TB; Kish, K; Jacobson, BL; Sheriff, S; Adam, LP; Ewing, WR; Robl, JA Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP). Bioorg Med Chem Lett 17:3511-5 (2007) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, heart
Synonyms:
FABP11 | FABP3 | FABPH_HUMAN | Fatty acid binding protein muscle | MDGI
Type:
PROTEIN
Mol. Mass.:
14858.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1463784
Residue:
133
Sequence:
MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
  
Inhibitor
Name:
BDBM50212886
Synonyms:
CHEMBL247529 | [2'-(3-ethyl-4,5-diphenyl-furan-2-yl)-biphenyl-3-yloxy]-acetic acid
Type:
Small organic molecule
Emp. Form.:
C32H26O4
Mol. Mass.:
474.5464
SMILES:
CCc1c(oc(c1-c1ccccc1)-c1ccccc1)-c1ccccc1-c1cccc(OCC(O)=O)c1
Structure:
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