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Target
Protein kinase C delta type
Ligand
BDBM50216856
Substrate
n/a
Meas. Tech.
ChEMBL_440176 (CHEMBL890490)
Ki
0.96±n/a nM
Citation
 Choi, Y; Pu, Y; Peach, ML; Kang, JH; Lewin, NE; Sigano, DM; Garfield, SH; Blumberg, PM; Marquez, VE Conformationally constrained analogues of diacylglycerol (DAG). 28. DAG-dioxolanones reveal a new additional interaction site in the C1b domain of PKC delta. J Med Chem 50:3465-81 (2007) [PubMed]  Article 
Target
Name:
Protein kinase C delta type
Synonyms:
KPCD_MOUSE | Pkcd | Prkcd | Protein kinase C delta | Protein kinase C delta type | nPKC-delta
Type:
PROTEIN
Mol. Mass.:
77554.99
Organism:
Mus musculus
Description:
ChEMBL_1351519
Residue:
674
Sequence:
MAPFLRISFNSYELGSLQVEDEASQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKTTFDAHIYEGRVIQIVLMRAAEDPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMCVQYFLEDGDCKQSMRSEEEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKEFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNSRDTIFQKERFNIDMPHRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRSSRKLDTTESVGIYQGFEKKPEVSGSDILDNNGTYGKIWEGSTRCTLENFTFQKVLGKGSFGKVLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEKRVLALAWESPFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHSKGIIYRDLKLDNVMLDRDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPDKRLGVTGNIRIHPFFKTINWSLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDKNLIDSMDQEAFHGFSFVNPKFEQFLDI
  
Inhibitor
Name:
BDBM50216856
Synonyms:
CHEMBL231617 | Z-{2-(Hydroxymethyl)-4-[5-methyl-3-(2-methylpropyl)hexylidene]-5-oxo-2-(2,3-dihydrofuryl)}methyl 3-Methylbutanoate
Type:
Small organic molecule
Emp. Form.:
C22H38O5
Mol. Mass.:
382.5341
SMILES:
CC(C)CC(C\C=C1\CC(CO)(COC(=O)CC(C)C)OC1=O)CC(C)C |w:9.11|
Structure:
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