Affinity DataKi: 0.140nM ΔG°: -54.9kJ/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.859nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of [3H]PDBu binding to C1b domain of protein kinase C delta with phosphatidylserineMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.960nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.15nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 1.16nM ΔG°: -49.8kJ/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of [3H]-PDBu binding to C1b domain of protein kinase C deltaMore data for this Ligand-Target Pair
Affinity DataKi: 1.21nMAssay Description:Binding affinity to mouse wildtype PKCdelta C1a expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity to PKCdeltaC1b in presence of phospholipidMore data for this Ligand-Target Pair
Affinity DataKi: 1.54nM ΔG°: -49.1kJ/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Affinity DataKi: 2.13nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.82nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 2.90nMpH: 7.4Assay Description:Inhibition of [3H]PDBu binding to recombinant protein kinase C alpha was determined at pH 7.4, 37 degree C for 5 minMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]PDBu from mouse recombinant PKCalpha expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 3.07nMAssay Description:Displacement of [3H]PDBu from mouse recombinant PKCalpha expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Inhibition of [3H]PDBu binding to C1b domain of protein kinase C delta with phosphatidylserineMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 3.30nMpH: 7.4Assay Description:Inhibition of [3H]PDBu binding to recombinant protein kinase C alpha was determined at pH 7.4, 37 degree C for 5 minMore data for this Ligand-Target Pair
Affinity DataKi: 3.49nMAssay Description:Displacement of [3H]PDBu from mouse recombinant PKCalpha expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.31nMAssay Description:Binding affinity to mouse wildtype PKCdelta C1a expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [20-3H]PDBU from recombinant PKCalpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.78nMAssay Description:Displacement of [3H]PDBu from mouse recombinant PKCalpha expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 5.90nM ΔG°: -45.9kJ/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]PDBu from mouse PKCdelta C1b Q27E mutant expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 6.41nMAssay Description:Displacement of [3H]PDBu from mouse recombinant PKCalpha expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nM ΔG°: -45.5kJ/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Displacement of [20-3H]PDBU from recombinant PKCalpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [20-3H]PDBU from recombinant PKCalpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Displacement of [20-3H]PDBU from recombinant PKCalpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Displacement of [20-3H]PDBU from recombinant PKCalpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Displacement of [20-3H]PDBU from recombinant PKCalpha in presence of phosphatidylserineMore data for this Ligand-Target Pair