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Target
D(1A) dopamine receptor
Ligand
BDBM50221673
Substrate
n/a
Meas. Tech.
ChEMBL_449680 (CHEMBL898784)
Ki
910±n/a nM
Citation
 Rodriguez Loaiza, P; Löber, S; Hübner, H; Gmeiner, P Click chemistry based solid phase supported synthesis of dopaminergic phenylacetylenes. Bioorg Med Chem 15:7248-57 (2007) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DRD1 | DRD1_PIG | Dopamine D1 receptor
Type:
PROTEIN
Mol. Mass.:
49269.92
Organism:
Sus scrofa
Description:
ChEMBL_1460140
Residue:
446
Sequence:
MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50221673
Synonyms:
CHEMBL394292 | N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}-4-ethynylbenzamide
Type:
Small organic molecule
Emp. Form.:
C23H25Cl2N3O
Mol. Mass.:
430.37
SMILES:
Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(cc3)C#C)CC2)c1Cl
Structure:
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