Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50030271
Substrate
n/a
Meas. Tech.
ChEMBL_548101 (CHEMBL1033450)
Ki
13700±n/a nM
Citation
 Eder, C; Schupp, P; Proksch, P; Wray, V; Steube, K; Müller, CE; Frobenius, W; Herderich, M; van Soest, RW Bioactive pyridoacridine alkaloids from the micronesian sponge Oceanapia sp. J Nat Prod 61:301-5 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50030271
Synonyms:
CHEMBL127872 | N-[2-(8H-6-Thia-3,4,8-triaza-benzo[de]cyclopenta[b]anthracen-7-yl)-ethyl]-acetamide | kuanoniamine D
Type:
Small organic molecule
Emp. Form.:
C20H16N4OS
Mol. Mass.:
360.432
SMILES:
CC(=O)NCCc1c2scnc2c2nccc3c4ccccc4[nH]c1c23
Structure:
Search PDB for entries with ligand similarity: