Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM50269843
Substrate
n/a
Meas. Tech.
ChEMBL_508373 (CHEMBL1005699)
IC50
100±n/a nM
Citation
 Giannini, C; Debitus, C; Lucas, R; Ubeda, A; Payá, M; Hooper, JN; D'Auria, MV New sesquiterpene derivatives from the sponge Dysidea species with a selective inhibitor profile against human phospholipase A2 and other leukocyte functions. J Nat Prod 64:612-5 (2001) [PubMed]  Article 
Target
Name:
Phospholipase A2
Synonyms:
Allergen Api m I | Allergen=Api m 1 | PA2_APIME | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2 (Bee)
Type:
PROTEIN
Mol. Mass.:
19061.47
Organism:
Apis mellifera
Description:
ChEMBL_1277435
Residue:
167
Sequence:
MQVVLGSLFLLLLSTSHGWQIRDRIGDNELEERIIYPGTLWCGHGNKSSGPNELGRFKHTDACCRTHDMCPDVMSAGESKHGLTNTASHTRLSCDCDDKFYDCLKNSADTISSYFVGKMYFNLIDTKCYKLEHPVTGCGERTEGRCLHYTVDKSKPKVYQWFDLRKY
  
Inhibitor
Name:
BDBM50269843
Synonyms:
Bolinaquinone | CHEMBL477692
Type:
Small organic molecule
Emp. Form.:
C22H30O4
Mol. Mass.:
358.4712
SMILES:
COC1=CC(=O)C(=O)C(C[C@@]2(C)CC[C@@]3(C)[C@@H](CCC=C3C)[C@H]2C)C1=O |r,c:19,t:2|
Structure:
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