Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50256742
Substrate
n/a
Meas. Tech.
ChEMBL_519599 (CHEMBL943674)
EC50
260±n/a nM
Citation
 Bharate, SB; Rodge, A; Joshi, RK; Kaur, J; Srinivasan, S; Kumar, SS; Kulkarni-Almeida, A; Balachandran, S; Balakrishnan, A; Vishwakarma, RA Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists. Bioorg Med Chem Lett 18:6357-61 (2008) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50256742
Synonyms:
CHEMBL475053 | sodium 2-(4-((2',6'-dimethylbiphenyl-3-yl)methoxy)benzyl)-3,5-dioxo-1,2,4-oxadiazolidin-4-ide
Type:
Small organic molecule
Emp. Form.:
C24H21N2O4
Mol. Mass.:
401.4351
SMILES:
Cc1cccc(C)c1-c1cccc(COc2ccc(Cn3oc(=O)[n-]c3=O)cc2)c1
Structure:
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