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Target
Free fatty acid receptor 1
Ligand
BDBM50005642
Substrate
n/a
Meas. Tech.
ChEMBL_519605 (CHEMBL946732)
EC50
6000±n/a nM
Citation
 Bharate, SB; Rodge, A; Joshi, RK; Kaur, J; Srinivasan, S; Kumar, SS; Kulkarni-Almeida, A; Balachandran, S; Balakrishnan, A; Vishwakarma, RA Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists. Bioorg Med Chem Lett 18:6357-61 (2008) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50005642
Synonyms:
1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis(3-methylbutan-1-one) | 3-Methyl-1-[2,4,6-trihydroxy-3-(3-methyl-butyryl)-phenyl]-butan-1-one | CHEMBL277845
Type:
Small organic molecule
Emp. Form.:
C16H22O5
Mol. Mass.:
294.3429
SMILES:
CC(C)CC(=O)c1c(O)cc(O)c(C(=O)CC(C)C)c1O
Structure:
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