Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50257958
Substrate
n/a
Meas. Tech.
ChEMBL_567040 (CHEMBL1029937)
EC50
35±n/a nM
Citation
 Zindell, R; Riether, D; Bosanac, T; Berry, A; Gemkow, MJ; Ebneth, A; Löbbe, S; Raymond, EL; Thome, D; Shih, DT; Thomson, D Morpholine containing CB2 selective agonists. Bioorg Med Chem Lett 19:1604-9 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50257958
Synonyms:
(S)-N-(4-fluorophenyl)-5-((2-phenylmorpholino)methyl)pyridin-2-amine | CHEMBL494029
Type:
Small organic molecule
Emp. Form.:
C22H22FN3O
Mol. Mass.:
363.428
SMILES:
Fc1ccc(Nc2ccc(CN3CCO[C@H](C3)c3ccccc3)cn2)cc1 |r|
Structure:
Search PDB for entries with ligand similarity: