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Target
Pepsin A
Ligand
BDBM201
Substrate
n/a
Meas. Tech.
ChEBML_153972
IC50
1000±n/a nM
Citation
 Fässler, A; Rösel, J; Grüther, M; Tintelnot-Blomley, M; Atteri, E; Bold, G; Lang, M Novel pseudosymmetric inhibitors of HIV-1 protease Bioorg Med Chem Lett 3:2837-2842 (1993)    Article 
Target
Name:
Pepsin A
Synonyms:
PEPA_PIG | PGA | Pepsin | Pepsin A precursor
Type:
Enzyme
Mol. Mass.:
41232.87
Organism:
Porcine
Description:
n/a
Residue:
385
Sequence:
MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALIGDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDSSTFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSDGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWILGDVFIRQYYTVFDRANNKVGLAPVA
  
Inhibitor
Name:
BDBM201
Synonyms:
(2S)-N-[(2S,3S)-4-[(2S)-N'-(cyclohexylmethyl)-2-acetamido-3-methylbutanehydrazido]-3-hydroxy-1-phenylbutan-2-yl]-2-acetamido-3-methylbutanamide | CGP 53820
Type:
n/a
Emp. Form.:
C31H51N5O5
Mol. Mass.:
573.7671
SMILES:
CC(C)[C@H](NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(CC1CCCCC1)NC(=O)[C@@H](NC(C)=O)C(C)C |r|
Structure:
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