Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50283251
Substrate
n/a
Meas. Tech.
ChEBML_48260
IC50
2.83±n/a nM
Citation
 Horwell, DC; Nichols, PD; Roberts, E Methionine replacements in biologically active peptides Bioorg Med Chem Lett 4:2263-2266 (1994)    Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50283251
Synonyms:
3-{(S)-2-[2-Amino-3-(1H-indol-3-yl)-propionylamino]-hept-5-enoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid | CHEMBL2369762
Type:
Small organic molecule
Emp. Form.:
C31H40N6O6
Mol. Mass.:
592.6859
SMILES:
CCCCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Structure:
Search PDB for entries with ligand similarity: