Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50283832
Substrate
n/a
Meas. Tech.
ChEBML_40039
IC50
1.1±n/a nM
Citation
 Lowe, JA; Qian, W; Scott, PJ; McLean, S; Bryce, DK; Crawford, RT; Bordner, J 5,7-Diphenyl-3-ureidohexahydroazepin-2-ones as Cholecystokinin-B receptor ligands Bioorg Med Chem Lett 4:2877-2882 (1994)    Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
n/a
Mol. Mass.:
48229.77
Organism:
Cavia porcellus
Description:
n/a
Residue:
430
Sequence:
MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50283832
Synonyms:
CHEMBL319504 | N-tert-Butyl-2-[(3R,5S,7R)-2-oxo-7-phenyl-5-p-tolyl-3-(3-m-tolyl-ureido)-azepan-1-yl]-acetamide
Type:
Small organic molecule
Emp. Form.:
C33H40N4O3
Mol. Mass.:
540.6957
SMILES:
Cc1ccc(cc1)[C@H]1C[C@@H](NC(=O)Nc2cccc(C)c2)C(=O)N(CC(=O)NC(C)(C)C)[C@H](C1)c1ccccc1
Structure:
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