Reaction Details Report a problem with these data
Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50012434
Substrate
n/a
Meas. Tech.
ChEBML_99989
Ki
8000±n/a nM
Citation
 Masamune, H; Eggler, JF; Marfat, A; Melvin, LS; Rusek, FW; Tickner, JE; Cheng, JB; Shirley, JT LTD4 Receptor binding activity of novel pyridine chromanols: qualitative correlation with pKa Bioorg Med Chem Lett 5:1371-1376 (1995)    Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50012434
Synonyms:
(REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol | 1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol | 1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol (RG 5901) | 1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hexan-1-ol(REV-5901) | CHEMBL8747 | REV-5901 | REV-901
Type:
Small organic molecule
Emp. Form.:
C22H25NO2
Mol. Mass.:
335.4394
SMILES:
CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1
Structure:
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