Reaction Details Report a problem with these data
Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50284683
Substrate
n/a
Meas. Tech.
ChEBML_99989
Ki
23400±n/a nM
Citation
 Masamune, H; Eggler, JF; Marfat, A; Melvin, LS; Rusek, FW; Tickner, JE; Cheng, JB; Shirley, JT LTD4 Receptor binding activity of novel pyridine chromanols: qualitative correlation with pKa Bioorg Med Chem Lett 5:1371-1376 (1995)    Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50284683
Synonyms:
(3S,4S)-6-(6-Chloro-pyridin-2-ylmethoxy)-3-pyridin-3-ylmethyl-chroman-4-ol | CHEMBL29937
Type:
Small organic molecule
Emp. Form.:
C21H19ClN2O3
Mol. Mass.:
382.84
SMILES:
O[C@H]1[C@@H](Cc2cccnc2)COc2ccc(OCc3cccc(Cl)n3)cc12
Structure:
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