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Target
Prostatic acid phosphatase
Ligand
BDBM50284954
Substrate
n/a
Meas. Tech.
ChEBML_148286
IC50
11000±n/a nM
Citation
 Schwender, CF; Beers, SA; Malloy, E; Demarest, K; Minor, L; Lau, KH 1-Naphthylmethylphosphonic acid derivatives as osteoclastic acid phosphatase inhibitors Bioorg Med Chem Lett 5:1801-1806 (1995)    Article 
Target
Name:
Prostatic acid phosphatase
Synonyms:
ACP3 | ACPP | PPAP_HUMAN | Prostatic acid phosphatase
Type:
PROTEIN
Mol. Mass.:
44563.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_158625
Residue:
386
Sequence:
MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
  
Inhibitor
Name:
BDBM50284954
Synonyms:
CHEMBL53536 | [2-Cyclohexyl-1-(2-methyl-naphthalen-1-yl)-ethyl]-phosphonic acid
Type:
Small organic molecule
Emp. Form.:
C19H25O3P
Mol. Mass.:
332.3738
SMILES:
Cc1ccc2ccccc2c1C(CC1CCCCC1)P(O)(O)=O
Structure:
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