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Target
Prostatic acid phosphatase
Ligand
BDBM50240513
Substrate
n/a
Meas. Tech.
ChEBML_148286
IC50
1400±n/a nM
Citation
 Schwender, CF; Beers, SA; Malloy, E; Demarest, K; Minor, L; Lau, KH 1-Naphthylmethylphosphonic acid derivatives as osteoclastic acid phosphatase inhibitors Bioorg Med Chem Lett 5:1801-1806 (1995)    Article 
Target
Name:
Prostatic acid phosphatase
Synonyms:
ACP3 | ACPP | PPAP_HUMAN | Prostatic acid phosphatase
Type:
PROTEIN
Mol. Mass.:
44563.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_158625
Residue:
386
Sequence:
MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
  
Inhibitor
Name:
BDBM50240513
Synonyms:
(1-Benzoyl-1-naphthalen-1-yl-2-oxo-2-phenyl-ethyl)-phosphonic acid | 2-(naphthalen-1-yl)-1,3-dioxo-1,3-diphenylpropan-2-ylphosphonic acid | CHEMBL300202
Type:
Small organic molecule
Emp. Form.:
C25H19O5P
Mol. Mass.:
430.3891
SMILES:
OP(O)(=O)C(C(=O)c1ccccc1)(C(=O)c1ccccc1)c1cccc2ccccc12
Structure:
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