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Target
Prostatic acid phosphatase
Ligand
BDBM50288667
Substrate
n/a
Meas. Tech.
ChEBML_158626
IC50
88000±n/a nM
Citation
 Schwender, CF; Beers, SA; Malloy, EA; Cinicola, JJ; Wustrow, DJ; Demarest, KD; Jordan, J Benzylphosphonic acid inhibitors of human prostatic acid phosphatase Bioorg Med Chem Lett 6:311-314 (1996)    Article 
Target
Name:
Prostatic acid phosphatase
Synonyms:
ACP3 | ACPP | PPAP_HUMAN | Prostatic acid phosphatase
Type:
PROTEIN
Mol. Mass.:
44563.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_158625
Residue:
386
Sequence:
MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
  
Inhibitor
Name:
BDBM50288667
Synonyms:
(3-Trifluoromethyl-benzyl)-phosphonic acid | CHEMBL104070
Type:
Small organic molecule
Emp. Form.:
C8H8F3O3P
Mol. Mass.:
240.1163
SMILES:
OP(O)(=O)Cc1cccc(c1)C(F)(F)F
Structure:
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