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Target
Carboxypeptidase A1
Ligand
BDBM50301283
Substrate
n/a
Meas. Tech.
ChEMBL_599273 (CHEMBL1041001)
Ki
160±n/a nM
Citation
 Wang, SF; Tian, GR; Zhang, WZ; Jin, JY Characterization of alpha-nitromethyl ketone as a new zinc-binding group based on structural analysis of its complex with carboxypeptidase A. Bioorg Med Chem Lett 19:5009-11 (2009) [PubMed]  Article 
Target
Name:
Carboxypeptidase A1
Synonyms:
CBPA1_HUMAN | CPA | CPA1
Type:
PROTEIN
Mol. Mass.:
47132.61
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1496378
Residue:
419
Sequence:
MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY
  
Inhibitor
Name:
BDBM50301283
Synonyms:
(R)-2-benzyl-5-nitro-4-oxopentanoic acid | CHEMBL571509
Type:
Small organic molecule
Emp. Form.:
C12H13NO5
Mol. Mass.:
251.2353
SMILES:
OC(=O)[C@@H](CC(=O)C[N+]([O-])=O)Cc1ccccc1 |r|
Structure:
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