Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 1
Ligand
BDBM50304581
Substrate
n/a
Meas. Tech.
ChEMBL_605126 (CHEMBL1064669)
Ki
311±n/a nM
Citation
 Fells, JI; Tsukahara, R; Liu, J; Tigyi, G; Parrill, AL Structure-based drug design identifies novel LPA3 antagonists. Bioorg Med Chem 17:7457-64 (2009) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 1
Synonyms:
EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2
Type:
Enzyme
Mol. Mass.:
41120.55
Organism:
Homo sapiens (Human)
Description:
Q92633
Residue:
364
Sequence:
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV
  
Inhibitor
Name:
BDBM50304581
Synonyms:
2-(1,3-dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic acid | CHEMBL607806
Type:
Small organic molecule
Emp. Form.:
C17H13NO5
Mol. Mass.:
311.2888
SMILES:
Cc1ccc(Oc2ccc3C(=O)N(CC(O)=O)C(=O)c3c2)cc1
Structure:
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