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Target
N-acylethanolamine-hydrolyzing acid amidase
Ligand
BDBM50171286
Substrate
n/a
Meas. Tech.
ChEMBL_608785 (CHEMBL1068377)
IC50
32000±n/a nM
Citation
 Saturnino, C; Petrosino, S; Ligresti, A; Palladino, C; De Martino, G; Bisogno, T; Di Marzo, V Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase. Bioorg Med Chem Lett 20:1210-3 (2010) [PubMed]  Article 
Target
Name:
N-acylethanolamine-hydrolyzing acid amidase
Synonyms:
ASAH-like protein | ASAHL | Acid ceramidase-like protein | N-acylethanolamine-hydrolyzing acid amidase | N-acylsphingosine amidohydrolase-like | N-acylsphingosine-amidohydrolase | NAAA | NAAA_HUMAN | PLT
Type:
Enzyme
Mol. Mass.:
40073.12
Organism:
Homo sapiens (Human)
Description:
Q02083
Residue:
359
Sequence:
MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
  
Inhibitor
Name:
BDBM50171286
Synonyms:
3-Hydroxy-N-pentadecyl-propionamide | CHEMBL423904 | N-(3-hydroxy-propionyl)pentadecanamide
Type:
Small organic molecule
Emp. Form.:
C18H37NO2
Mol. Mass.:
299.4919
SMILES:
CCCCCCCCCCCCCCCNC(=O)CCO
Structure:
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