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Target
Adenosine receptor A2a
Ligand
BDBM50318246
Substrate
n/a
Meas. Tech.
ChEMBL_629286 (CHEMBL1117497)
Ki
1300±n/a nM
Citation
 Carlsson, J; Yoo, L; Gao, ZG; Irwin, JJ; Shoichet, BK; Jacobson, KA Structure-based discovery of A2A adenosine receptor ligands. J Med Chem 53:3748-55 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50318246
Synonyms:
CHEMBL1097073 | N-(4,6-dimethylpyrimidin-2-yl)-6-methyl-1H-benzo[d]imidazol-2-amine
Type:
Small organic molecule
Emp. Form.:
C14H15N5
Mol. Mass.:
253.3024
SMILES:
Cc1ccc2nc(Nc3nc(C)cc(C)n3)[nH]c2c1
Structure:
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