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Target
Adenosine receptor A2a
Ligand
BDBM50318249
Substrate
n/a
Meas. Tech.
ChEMBL_629286 (CHEMBL1117497)
Ki
8800±n/a nM
Citation
 Carlsson, J; Yoo, L; Gao, ZG; Irwin, JJ; Shoichet, BK; Jacobson, KA Structure-based discovery of A2A adenosine receptor ligands. J Med Chem 53:3748-55 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50318249
Synonyms:
(E)-N-(amino(4-methylquinazolin-2-ylamino)methylene)-2-(methylamino)benzamide | CHEMBL1094646
Type:
Small organic molecule
Emp. Form.:
C18H18N6O
Mol. Mass.:
334.3751
SMILES:
CNc1ccccc1C(=O)NC(N)=Nc1nc(C)c2ccccc2n1 |w:13.14|
Structure:
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