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Target
Adenosine receptor A3
Ligand
BDBM50102282
Substrate
n/a
Meas. Tech.
ChEMBL_685065 (CHEMBL1286681)
Ki
>1000±n/a nM
Citation
 Giovannoni, MP; Vergelli, C; Cilibrizzi, A; Crocetti, L; Biancalani, C; Graziano, A; Dal Piaz, V; Loza, MI; Cadavid, MI; Díaz, JL; Gavaldà, A Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A(1) adenosine receptor ligands. Bioorg Med Chem 18:7890-9 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
AA3R_BOVIN | ADORA3
Type:
PROTEIN
Mol. Mass.:
35924.51
Organism:
Bos taurus
Description:
ChEMBL_685065
Residue:
317
Sequence:
MPVNSTAVSLASVTYISVEILIGLCAIVGNVLVIWVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVISLGVTIHFYSCLLMTCLLMIFTHASIMSLLAIAVDRYLRVKLTVRYRRVTTQRRIWLALGLCWLVSFLVGLTPMFGWNMKLSSADKNLTFLPCQFRSVMRMDYMVYFSFFTWILIPLVVMCAIYFDIFYVIRNRLSQNFSGSKETGAFYGREFKTAKSLSLVLFLFALSWLPLSIINCIIYFNGEVPQIVLYLGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVICQPSKSMDPSIEQTSE
  
Inhibitor
Name:
BDBM50102282
Synonyms:
3,10-Diphenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one | CHEMBL112756
Type:
Small organic molecule
Emp. Form.:
C21H14N4O
Mol. Mass.:
338.3621
SMILES:
O=c1c(nnc2n(-c3ccccc3)c3ccccc3n12)-c1ccccc1
Structure:
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