Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50335736
Substrate
n/a
Meas. Tech.
ChEMBL_715074 (CHEMBL1664180)
Ki
15.6±n/a nM
Citation
 Yaziji, V; Rodríguez, D; Gutiérrez-de-Terán, H; Coelho, A; Caamaño, O; García-Mera, X; Brea, J; Loza, MI; Cadavid, MI; Sotelo, E Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists. J Med Chem 54:457-71 (2011) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50335736
Synonyms:
CHEMBL1650382 | N-2,6-distyrylpyrimidin-4-yl)acetamide
Type:
Small organic molecule
Emp. Form.:
C22H19N3O
Mol. Mass.:
341.4058
SMILES:
CC(=O)Nc1cc(\C=C\c2ccccc2)nc(\C=C\c2ccccc2)n1
Structure:
Search PDB for entries with ligand similarity: