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Target
Glutathione S-transferase
Ligand
BDBM4078
Substrate
n/a
Meas. Tech.
ChEMBL_729209 (CHEMBL1694673)
IC50
74400±n/a nM
Citation
 Sturm, N; Hu, Y; Zimmermann, H; Fritz-Wolf, K; Wittlin, S; Rahlfs, S; Becker, K Compounds structurally related to ellagic acid show improved antiplasmodial activity. Antimicrob Agents Chemother 53:622-30 (2009) [PubMed]  Article 
Target
Name:
Glutathione S-transferase
Synonyms:
GST | GST_PLAF7 | PfGST
Type:
PROTEIN
Mol. Mass.:
24788.28
Organism:
Plasmodium falciparum
Description:
ChEMBL_729209
Residue:
211
Sequence:
MGDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDTPFEQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNLFKQNETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETKYPSSLKNFPLLKAHNEFISNLPNIKNYITNRKESVY
  
Inhibitor
Name:
BDBM4078
Synonyms:
6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(14),4(16),5,7,11(15),12-hexaene-3,10-dione | CHEMBL6246 | ELLAGIC ACID | Elagic Acid | Ellagic acid (18) | Ellagic acid dihydrate | MLS000069632 | SMR000058244 | cid_5281855
Type:
Small organic molecule
Emp. Form.:
C14H6O8
Mol. Mass.:
302.1926
SMILES:
Oc1cc2c3c(oc(=O)c4cc(O)c(O)c(oc2=O)c34)c1O
Structure:
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