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Target
D(1A) dopamine receptor
Ligand
BDBM50132080
Substrate
n/a
Meas. Tech.
ChEMBL_742111 (CHEMBL1769066)
Ki
570±n/a nM
Citation
 Tschammer, N; Elsner, J; Goetz, A; Ehrlich, K; Schuster, S; Ruberg, M; Kühhorn, J; Thompson, D; Whistler, J; Hübner, H; Gmeiner, P Highly potent 5-aminotetrahydropyrazolopyridines: enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions. J Med Chem 54:2477-91 (2011) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DRD1 | DRD1_PIG | Dopamine D1 receptor
Type:
PROTEIN
Mol. Mass.:
49269.92
Organism:
Sus scrofa
Description:
ChEMBL_1460140
Residue:
446
Sequence:
MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50132080
Synonyms:
Biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide; oxalic acid | CHEMBL112065 | CHEMBL129483
Type:
Small organic molecule
Emp. Form.:
C28H33N3O2
Mol. Mass.:
443.5805
SMILES:
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)-c2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: