Affinity DataKi: 0.0270nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0760nMAssay Description:Displacement of [3H]spiperone from wild type human dopamine D3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.590nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]spiperone from wild type human dopamine D3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2long receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
New York University
Curated by ChEMBL
New York University
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]-haloperidol in the presence of 25 nM unlabeled spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]spiperone from wild type human dopamine D3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]spiperone from wild type human dopamine D3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2long receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.80nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
New York University
Curated by ChEMBL
New York University
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]- haloperidolMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
New York University
Curated by ChEMBL
New York University
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]- haloperidolMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]spiperone from wild type human dopamine D3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Displacement of [3H]spiperone from human dopamine D2short receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [3H]spiperone from human dopamine D2short receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Displacement of [3H]spiperone from wild type human dopamine D3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2long receptor expressed in CHO cells after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair