Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50341516
Substrate
n/a
Meas. Tech.
ChEMBL_742224 (CHEMBL1768394)
Ki
2.7±n/a nM
Citation
 Tschammer, N; Elsner, J; Goetz, A; Ehrlich, K; Schuster, S; Ruberg, M; Kühhorn, J; Thompson, D; Whistler, J; Hübner, H; Gmeiner, P Highly potent 5-aminotetrahydropyrazolopyridines: enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions. J Med Chem 54:2477-91 (2011) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50341516
Synonyms:
CHEMBL1765637 | N-[(N'-Indan-2-yl-N'-propyl)-4-aminobutyl]phenylcarboxamide
Type:
Small organic molecule
Emp. Form.:
C24H32N2O
Mol. Mass.:
364.5237
SMILES:
CCCN(CCCCNC(=O)Cc1ccccc1)C1Cc2ccccc2C1
Structure:
Search PDB for entries with ligand similarity: