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Target
Cannabinoid receptor 2
Ligand
BDBM50341951
Substrate
n/a
Meas. Tech.
ChEMBL_743428 (CHEMBL1767782)
IC50
6.3±n/a nM
Citation
 Manley, PJ; Zartman, A; Paone, DV; Burgey, CS; Henze, DA; Della Penna, K; Desai, R; Leitl, MD; Lemaire, W; White, RB; Yeh, S; Urban, MO; Kane, SA; Hartman, GD; Bilodeau, MT; Trotter, BW Decahydroquinoline amides as highly selective CB2 agonists: role of selectivity on in vivo efficacy in a rodent model of analgesia. Bioorg Med Chem Lett 21:2359-64 (2011) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2
Type:
Enzyme
Mol. Mass.:
39366.68
Organism:
Rattus norvegicus (Rat)
Description:
Q9QZN9
Residue:
360
Sequence:
MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
  
Inhibitor
Name:
BDBM50341951
Synonyms:
((4S,4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-1(2H)-yl)(6-methylpyridin-3-yl)methanone | CHEMBL1765276 | cis-rac-((4S,4aR,8aS)-4-hydroxy-4-phenyloctahydroquinolin-1(2H)-yl)(6-methylpyridin-3-yl)methanone
Type:
Small organic molecule
Emp. Form.:
C22H26N2O2
Mol. Mass.:
350.454
SMILES:
Cc1ccc(cn1)C(=O)N1CC[C@](O)([C@@H]2CCCC[C@H]12)c1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: