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Target
Free fatty acid receptor 1
Ligand
BDBM50343141
Substrate
n/a
Meas. Tech.
ChEMBL_745322 (CHEMBL1775397)
EC50
19±n/a nM
Citation
 Christiansen, E; Due-Hansen, ME; Urban, C; Merten, N; Pfleiderer, M; Karlsen, KK; Rasmussen, SS; Steensgaard, M; Hamacher, A; Schmidt, J; Drewke, C; Petersen, RK; Kristiansen, K; Ullrich, S; Kostenis, E; Kassack, MU; Ulven, T Structure-Activity Study of Dihydrocinnamic Acids and Discovery of the Potent FFA1 (GPR40) Agonist TUG-469. ACS Med Chem Lett 1:345-349 (2010) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1_MOUSE | Ffar1 | Gpr40
Type:
PROTEIN
Mol. Mass.:
31818.80
Organism:
Mus musculus
Description:
ChEMBL_1454431
Residue:
300
Sequence:
MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLGCSDLLLAITLPLKAVEALASGAWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPRYSWGVCVAIWALVLCHLGLALGLETSGSWLDNSTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVRSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLGGSWRKLGLITGAWSVVLNPLVTGYLGTGPGRGTICVTRTQRGTIQK
  
Inhibitor
Name:
BDBM50343141
Synonyms:
3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)propanoic acid | CHEMBL1773261
Type:
Small organic molecule
Emp. Form.:
C23H23NO2
Mol. Mass.:
345.4342
SMILES:
Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1
Structure:
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