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Target
Peptide deformylase
Ligand
BDBM50347025
Substrate
n/a
Meas. Tech.
ChEMBL_753600 (CHEMBL1799317)
IC50
70±n/a nM
Citation
 East, SP; Ayscough, A; Toogood-Johnson, I; Taylor, S; Thomas, W Peptidomimetic inhibitors of bacterial peptide deformylase. Bioorg Med Chem Lett 21:4032-5 (2011) [PubMed]  Article 
Target
Name:
Peptide deformylase
Synonyms:
3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2
Type:
n/a
Mol. Mass.:
16901.39
Organism:
Escherichia coli
Description:
n/a
Residue:
150
Sequence:
MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIGLRLGNGKYCTLRLFFNQV
  
Inhibitor
Name:
BDBM50347025
Synonyms:
CHEMBL1796085
Type:
Small organic molecule
Emp. Form.:
C20H27N3O4
Mol. Mass.:
373.4461
SMILES:
ON(C[C@@H](CC1CCCC1)C(=O)N1CCCN1C(=O)c1ccccc1)C=O |r|
Structure:
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