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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50349866
Substrate
n/a
Meas. Tech.
ChEMBL_760694 (CHEMBL1815679)
Ki
1176±n/a nM
Citation
 Vangveravong, S; Zhang, Z; Taylor, M; Bearden, M; Xu, J; Cui, J; Wang, W; Luedtke, RR; Mach, RH Synthesis and characterization of selective dopamine D2 receptor ligands using aripiprazole as the lead compound. Bioorg Med Chem 19:3502-11 (2011) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50349866
Synonyms:
CHEMBL160296 | CHEMBL1813590 | UNC10108016 | US9156822, 39
Type:
Small organic molecule
Emp. Form.:
C24H31N3O3
Mol. Mass.:
409.5212
SMILES:
COc1ccccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1
Structure:
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