Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50349871
Substrate
n/a
Meas. Tech.
ChEMBL_760694 (CHEMBL1815679)
Ki
20904±n/a nM
Citation
 Vangveravong, S; Zhang, Z; Taylor, M; Bearden, M; Xu, J; Cui, J; Wang, W; Luedtke, RR; Mach, RH Synthesis and characterization of selective dopamine D2 receptor ligands using aripiprazole as the lead compound. Bioorg Med Chem 19:3502-11 (2011) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50349871
Synonyms:
CHEMBL1813595
Type:
Small organic molecule
Emp. Form.:
C25H30FN3O3
Mol. Mass.:
439.5224
SMILES:
FCCOc1ccccc1N1CCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1
Structure:
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