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Target
Galanin receptor type 1
Ligand
BDBM50358671
Substrate
n/a
Meas. Tech.
ChEMBL_789438 (CHEMBL1924414)
IC50
6820±n/a nM
Citation
 Sagi, VN; Liu, T; Lu, X; Bartfai, T; Roberts, E Synthesis and biological evaluation of novel pyrimidine derivatives as sub-micromolar affinity ligands of GalR2. Bioorg Med Chem Lett 21:7210-5 (2011) [PubMed]  Article 
Target
Name:
Galanin receptor type 1
Synonyms:
GAL1-R | GALNR | GALNR1 | GALR1 | GALR1_HUMAN | Galanin R1 | Galanin receptor 1 | Galanin receptor type 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38976.60
Organism:
Homo sapiens (Human)
Description:
Galanin R1 GALR1 HUMAN::P47211
Residue:
349
Sequence:
MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV
  
Inhibitor
Name:
BDBM50358671
Synonyms:
CHEMBL1922023
Type:
Small organic molecule
Emp. Form.:
C28H29FN6O2
Mol. Mass.:
500.5673
SMILES:
COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(n2)N2CCN(CC2)c2ccccc2)cc1
Structure:
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