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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50360740
Substrate
n/a
Meas. Tech.
ChEMBL_796451 (CHEMBL1937766)
EC50
13000±n/a nM
Citation
 Nomura, M; Yumoto, K; Shinozaki, T; Isogai, S; Takano, Y; Murakami, K Discovery of cyclic amine-substituted benzoic acids as PPARa agonists. Bioorg Med Chem Lett 22:334-8 (2011) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
Nr1c3 | PPARG_RAT | Pparg
Type:
PROTEIN
Mol. Mass.:
57562.54
Organism:
Rattus norvegicus
Description:
ChEMBL_642067
Residue:
505
Sequence:
MGETLGDPPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMDDHSHSFDIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQLLHVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50360740
Synonyms:
CHEMBL1934476
Type:
Small organic molecule
Emp. Form.:
C23H22ClN3O3S
Mol. Mass.:
455.957
SMILES:
Cc1nc(sc1C(=O)N[C@H]1CCCN(C1)c1cccc(c1)C(O)=O)-c1ccc(Cl)cc1 |r|
Structure:
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