TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of Escherichia coli LpxC using UDP-3-O-(R-3-hydroxymyristoyl)GlcNAc as substrate measured after 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of human dUTPase assessed as reduction in [5-3H]dUMP production incubated for 15 mins by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair