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Target
Prostaglandin D2 receptor 2
Ligand
BDBM50362156
Substrate
n/a
Meas. Tech.
ChEMBL_797760 (CHEMBL1944119)
IC50
147±n/a nM
Citation
 Ito, S; Terasaka, T; Zenkoh, T; Matsuda, H; Hayashida, H; Nagata, H; Imamura, Y; Kobayashi, M; Takeuchi, M; Ohta, M Discovery of novel and potent CRTH2 antagonists. Bioorg Med Chem Lett 22:1194-7 (2012) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor 2
Synonyms:
Chemoattractant receptor-homologous molecule expressed on Th2 cells
Type:
PROTEIN
Mol. Mass.:
42241.65
Organism:
Cavia porcellus
Description:
ChEMBL_797760
Residue:
391
Sequence:
MANATLKPLCPVLKDMSLLGSHSNSSLRYMDHISVLLHGLAALLGLVENGLIVFVVGCRMRQTVVTTWALHLALSDLLASAALPFFTYFLAVGHSWELGTAFCKLHSSVFFLNMFASGFLLSAISLDRCVRVVHPVWAQNHRSVSVARRVCAVLWALALLNTVPYFVFRDTILRRDGRTMCYYNVLLLAPAGDHNATCGTRQMALALSKFLLAFALPLGIIAASHAVVSARLQRRPQGGVRPGRFVRLVAAVVAAFALCWGPYHAFSLIEARAHAVPSLRPLAWRALPFVSSLAFINSVVNPLLYVLTCPDVGRKLRRSLRAVLESVLVDDGELGSRYRRRGGSSSPAVASASSSLSLAPATHQACSLLRWLRGSRGTGSDDAPSSASGQG
  
Inhibitor
Name:
BDBM50362156
Synonyms:
CHEMBL1941117
Type:
Small organic molecule
Emp. Form.:
C28H26N2O4
Mol. Mass.:
454.517
SMILES:
OC(=O)COc1cccc(CCCn2nc(ccc2=O)C(c2ccccc2)c2ccccc2)c1
Structure:
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