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Target
Platelet-activating factor receptor
Ligand
BDBM50282032
Substrate
n/a
Meas. Tech.
ChEBML_155135
IC50
20±n/a nM
Citation
 Wood, L; Whittaker, M; Timmis, DJ; Thompson, TM; Saroglou, L; Miller, A; Davidson, AH; Christodoulou, MS; Cackett, KS; Bowles, SA; Bebbington, DS Cyclic ether acetal platelet activating factor (PAF) receptor antagonists II: imidazo[4,5-c]pyridyl derivatives Bioorg Med Chem Lett 3:1499-1504 (1993)    Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39219.60
Organism:
Homo sapiens (Human)
Description:
PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:
342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
  
Inhibitor
Name:
BDBM50282032
Synonyms:
2-Methyl-1-{3-[5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yloxy]-propyl}-1H-imidazo[4,5-c]pyridine | CHEMBL34182
Type:
Small organic molecule
Emp. Form.:
C23H29N3O5
Mol. Mass.:
427.4935
SMILES:
COc1cc(cc(OC)c1OC)C1CCC(OCCCn2c(C)nc3cnccc23)O1
Structure:
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