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Target
B2 bradykinin receptor
Ligand
BDBM50286366
Substrate
n/a
Meas. Tech.
ChEBML_40427
Ki
2540±n/a nM
Citation
 Salvino, JM; Seoane, PR; Douty, BD; Awad, MA; Hoyer, D; Ross, TM; Dolle, RE; Houck, WT; Faunce, DM; Sawutz, DG Structure activity relationships of non-peptide bradykinin B2 receptor antagonists Bioorg Med Chem Lett 5:357-362 (1995)    Article 
Target
Name:
B2 bradykinin receptor
Synonyms:
B2 BRADYKININ | B2 bradykinin receptor | B2R | BDKRB2 | BK-2 receptor | BKR2 | BKRB2_HUMAN | Bradykinin B2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44467.17
Organism:
Homo sapiens (Human)
Description:
B2 BRADYKININ BDKRB2 HUMAN::P30411
Residue:
391
Sequence:
MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEPIQMENSMGTLRTSISVERQIHKLQDWAGSRQ
  
Inhibitor
Name:
BDBM50286366
Synonyms:
2-(N',N''-Dicyclohexyl-guanidino)-N-isoquinolin-8-yl-3-naththalen-2-yl-propionamide
Type:
Small organic molecule
Emp. Form.:
C35H42N5O
Mol. Mass.:
548.7403
SMILES:
O=C(Nc1cccc2ccncc12)[C@@H](Cc1ccc2ccccc2c1)N\C(NC1CCCCC1)=[NH+]\C1CCCCC1
Structure:
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