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Target
D(2) dopamine receptor
Ligand
BDBM50044235
Substrate
n/a
Meas. Tech.
ChEMBL_61440 (CHEMBL671413)
IC50
9510±n/a nM
Citation
 Wikström, H; Andersson, B; Svensson, A; Humber, LG; Asselin, AA; Svensson, K; Ekman, A; Carlsson, A; Nilsson, I; Chidester, C Resolved 6,7,8,9-tetrahydro-N,N-dimethyl-3H-benz[e]indol-8-amine: central dopamine and serotonin receptor stimulating properties. J Med Chem 32:2273-6 (1989) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50044235
Synonyms:
CHEMBL292274 | Dimethyl-(S)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine | S-(-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
Type:
Small organic molecule
Emp. Form.:
C14H18N2
Mol. Mass.:
214.3061
SMILES:
CN(C)[C@H]1CCc2ccc3[nH]ccc3c2C1
Structure:
Search PDB for entries with ligand similarity: