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Target
Prostaglandin-H2 D-isomerase
Ligand
BDBM50009861
Substrate
n/a
Meas. Tech.
ChEBML_158157
IC50
12000±n/a nM
Citation
 Bell, MR; D'Ambra, TE; Kumar, V; Eissenstat, MA; Herrmann, JL; Wetzel, JR; Rosi, D; Philion, RE; Daum, SJ; Hlasta, DJ Antinociceptive (aminoalkyl)indoles. J Med Chem 34:1099-110 (1991) [PubMed]  Article 
Target
Name:
Prostaglandin-H2 D-isomerase
Synonyms:
PTGDS_MOUSE | Ptgds
Type:
PROTEIN
Mol. Mass.:
21069.88
Organism:
Mus musculus
Description:
ChEMBL_158158
Residue:
189
Sequence:
MAALRMLWMGLVLLGLLGFPQTPAQGHDTVQPNFQQDKFLGRWYSAGLASNSSWFREKKAVLYMCKTVVAPSTEGGLNLTSTFLRKNQCETKIMVLQPAGAPGHYTYSSPHSGSIHSVSVVEANYDEYALLFSRGTKGPGQDFRMATLYSRTQTLKDELKEKFTTFSKAQGLTEEDIVFLPQPDKCIQE
  
Inhibitor
Name:
BDBM50009861
Synonyms:
(2-Fluoro-phenyl)-[1-(1-methyl-2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone | (R)(2-Fluoro-phenyl)-[1-(1-methyl-2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone | (S) (2-Fluoro-phenyl)-[1-(1-methyl-2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone | CHEMBL13463
Type:
Small organic molecule
Emp. Form.:
C22H23FN2O2
Mol. Mass.:
366.4286
SMILES:
CC(CN1CCOCC1)n1cc(C(=O)c2ccccc2F)c2ccccc12
Structure:
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