Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50453224
Substrate
n/a
Meas. Tech.
ChEMBL_29156 (CHEMBL637705)
Ki
44±n/a nM
Citation
 Cristalli, G; Eleuteri, A; Vittori, S; Volpini, R; Lohse, MJ; Klotz, KN 2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors. J Med Chem 35:2363-8 (1992) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50453224
Synonyms:
2-(l-hexyn-l-yl)-adenosine-5'-N-methyluronamide (16c) | CHEMBL410873
Type:
Small organic molecule
Emp. Form.:
C18H24N6O4
Mol. Mass.:
388.421
SMILES:
CCCCC#Cc1nc(N)c2ncn([C@@H]3O[C@@H]([C@@H](O)[C@H]3O)C(=O)NCC)c2n1
Structure:
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