Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50040079
Substrate
n/a
Meas. Tech.
ChEBML_61346
Ki
0.160000±n/a nM
Citation
 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH 18F-labeled benzamides for studying the dopamine D2 receptor with positron emission tomography. J Med Chem 36:3707-20 (1994) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50040079
Synonyms:
CHEMBL308524 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-5,6-dimethoxy-benzamide (ioxipride) | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-5,6-dimethoxy-benzamide( NCQ 298)
Type:
Small organic molecule
Emp. Form.:
C16H23IN2O4
Mol. Mass.:
434.2693
SMILES:
CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)cc(OC)c1OC
Structure:
Search PDB for entries with ligand similarity: