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Target
Adenosine receptor A1
Ligand
BDBM50453505
Substrate
n/a
Meas. Tech.
ChEMBL_29165 (CHEMBL637896)
Ki
150±n/a nM
Citation
 Güngör, T; Malabre, P; Teulon, JM; Camborde, F; Meignen, J; Hertz, F; Virone-Oddos, A; Caussade, F; Cloarec, A N6-substituted adenosine receptor agonists. Synthesis and pharmacological activity as potent antinociceptive agents. J Med Chem 37:4307-16 (1995) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50453505
Synonyms:
CHEMBL2113589
Type:
Small organic molecule
Emp. Form.:
C32H34ClN7O4
Mol. Mass.:
616.11
SMILES:
Cc1ccc(C)c(Cn2cc(CCNc3ncnc4n(cnc34)[C@@H]3O[C@@H]([C@@H](O)[C@H]3O)C(=O)NC3CC3)c3cc(Cl)ccc23)c1 |r|
Structure:
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