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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50041044
Substrate
n/a
Meas. Tech.
ChEMBL_159300 (CHEMBL769406)
IC50
>10000±n/a nM
Citation
 Greer, J; Erickson, JW; Baldwin, JJ; Varney, MD Application of the three-dimensional structures of protein target molecules in structure-based drug design. J Med Chem 37:1035-54 (1994) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50041044
Synonyms:
(2S,4S)-2,4-Diamino-1,5-diphenyl-pentan-3-ol | 2,4-DIAMINO-1,5-DIPHENYL-3-HYDROXYPENTANE | CHEMBL9417
Type:
Small organic molecule
Emp. Form.:
C17H22N2O
Mol. Mass.:
270.3694
SMILES:
N[C@@H](Cc1ccccc1)C(O)[C@@H](N)Cc1ccccc1
Structure:
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