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Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM50451023
Substrate
n/a
Meas. Tech.
ChEMBL_2844 (CHEMBL617866)
Ki
5.2±n/a nM
Citation
 Anzini, M; Cappelli, A; Vomero, S; Giorgi, G; Langer, T; Hamon, M; Merahi, N; Emerit, BM; Cagnotto, A; Skorupska, M Novel, potent, and selective 5-HT3 receptor antagonists based on the arylpiperazine skeleton: synthesis, structure, biological activity, and comparative molecular field analysis studies. J Med Chem 38:2692-704 (1995) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
Type:
Enzyme
Mol. Mass.:
51935.10
Organism:
Rattus norvegicus (Rat)
Description:
P08909
Residue:
460
Sequence:
MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
  
Inhibitor
Name:
BDBM50451023
Synonyms:
MESULERGINE
Type:
Small organic molecule
Emp. Form.:
C19H28N4O2S
Mol. Mass.:
376.516
SMILES:
[H][C@@]12Cc3cn(C)c4cccc(c34)[C@@]1([H])C[C@H](CNS(=O)(=O)N(C)C)CN2C |r|
Structure:
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