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Target
5-hydroxytryptamine receptor 3B
Ligand
BDBM50056946
Substrate
n/a
Meas. Tech.
ChEMBL_3122
Ki
3160±n/a nM
Citation
 el Ahmad, Y; Laurent, E; Maillet, P; Talab, A; Teste, JF; Dokhan, R; Tran, G; Ollivier, R New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands. J Med Chem 40:952-60 (1997) [PubMed]  Article
Target
Name:
5-hydroxytryptamine receptor 3B
Synonyms:
Serotonin 3 receptor (5HT3) | Serotonin 3b (5-HT3b) receptor
Type:
PROTEIN
Mol. Mass.:
50317.35
Organism:
Mus musculus
Description:
ChEMBL_3121
Residue:
437
Sequence:
MILLWSCLLVAVVGILGTATPQPGNSSLHRLTRQLLQQYHKEVRPVYNWAEATTVYLDLCVHAVLDVDVQNQKLKTSVWYREVWNDEFLSWNSSLFDEIQEISLPLSALWAPDIIINEFVDVERSPDLPYVYVNSSGTIRNHKPIQVVSACSLQTYAFPFDIQNCSLTFNSILHTVEDIDLGFLRNREDIENDKRAFMNDSEWQLLSVSSTYHIRQSSAGDFAQIRFNVVIRRCPLAYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTNVLVGYTVFRVNMSDEVPRSAGCTPLIGVFFTVCMALLVLSLSKSILLIKFLYEERHSGQERPLMCLQGDSDAEESRLYLGAPRADVTESPVHQEHRVPSDTLKDFWFQFRSINNSLRTRDQIHQKEVEWLAILYRFDQLLFRIYLAVLGLYTVTLCSLWALWSRM
  
Inhibitor
Name:
BDBM50056946
Synonyms:
1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-naphthalen-1-yl)-piperazin-1-yl]-butan-1-one | CHEMBL366388
Type:
Small organic molecule
Emp. Form.:
C24H29FN2O
Mol. Mass.:
380.4983
SMILES:
Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12
Structure:
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