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Target
Beta-lactamase
Ligand
BDBM50111604
Substrate
n/a
Meas. Tech.
ChEMBL_40260 (CHEMBL877274)
IC50
5000±n/a nM
Citation
 McGovern, SL; Helfand, BT; Feng, B; Shoichet, BK A specific mechanism of nonspecific inhibition. J Med Chem 46:4265-72 (2003) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC
Type:
Protien
Mol. Mass.:
41561.62
Organism:
Escherichia coli
Description:
P00811
Residue:
377
Sequence:
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ
  
Inhibitor
Name:
BDBM50111604
Synonyms:
3-[(4-Phenoxy-phenylamino)-methylene]-3H-isobenzofuran-1-one | 3-[1-(4-Phenoxy-phenylamino)-meth-(Z)-ylidene]-3H-isobenzofuran-1-one | CHEMBL430923
Type:
Small organic molecule
Emp. Form.:
C21H15NO3
Mol. Mass.:
329.3487
SMILES:
Oc1oc(\C=N\c2ccc(Oc3ccccc3)cc2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: